Cancer nanotherapeutics, extracellular vesicles, biosensors, cancer liquid biopsy
Grants and Sponsored Research
September 2022–August 2027 Lung cancer early detection and immunotherapy response prediction and monitoring with an Exo-PROS liquid biopsy assay NCI Role: Principal Investigator $3,120,685
April 2023–March 2027 Multifunctional Biodegradable Zwitterionic Polymer-Drug Conjugates for Multidrug NIBIB Role: Co-Investigator $2,388,081
July 2022–June 2024 Exosomal Thomsen-Friedenreich glycoantigen as a new biomarker for lung cancer screening and early detection NCI Role: Principal Investigator $431,992
August 2020–July 2023 An inflammation-induced fibrosis-on-chip system for the testing of anti-fibrosis drugs NHLBI Role: Co-Investigator $920,000
September 2021–June 2023 Zwitterionic dendrimer-modified PEG for protein conjugation NIBIB Role: Co-Principal Investigator $433,902
March 2019–February 2023 Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection NCI Role: Principal Investigator $565,427
September 2019–August 2022 Exosome Protein microRNA One Stop (Exo-PROS) biosensor: a new liquid biopsy for precision cancer immunotherpay Cancer Research Institute Role: Principal Investigator $200,000
September 2017–February 2022 PFI: BIC: WearNet: Smart Health Monitoring & Diagnosis System Based on Wearable Nano-biosensing Networks NSF Role: Co-Principal Investigator $1,047,141
October 2019–December 2021 Development of Tumor Targeted Nanoparticles to Combat EGFR TKI Resistance American Lung Association Role: Co-Principal Investigator $200,000
September 2015–August 2021 Noninvasive Detection of Circulating RNAs for Lung Cancer Early Detection and Prognosis NCI Role: Principal Investigator $1,279,946
September 2015–May 2021 Fibrotic Microtissue Chips for Screening of Anti-fibrotic Therapies NIBIB Role: Co-Investigator $1,407,173
September 2016–August 2020 Cationic Diblock Polymer-Drug Conjugate-Based Nanoparticles for Drug-Gene Co-Delivery NSF Role: Co-Principal Investigator $420,000