Hui Meng
PhD
UB Distinguished Professor
Research Interests
Biomedical engineering; hemodynamics and vascular biomechanics; advanced laser flow diagnostics; computational fluid dynamics
Selected Publications
- Abdehkakha A, Hammond AL, Patel TR, Siddiqui AH, Dargush GF, Meng H: Cerebral aneurysm flow diverter modeled as a thin inhomogeneous porous medium in hemodynamic simulations, Computers in Biology and Medicine, 2021-12-01, 139. PMID: 34717230. https://doi.org/10.1016/j.compbiomed.2021.104988
- Patel P, Sarayi S, Chen D, Hammond AL, Damiano RJ, Davies JM, Xu J, Meng H: Fast virtual coiling algorithm for intracranial aneurysms using pre-shape path planning, Computers in Biology and Medicine 2021,134. PMID: 34077817. https://doi.org/10.1016/j.compbiomed.2021.104496
- Tutino VM, Rajabzadeh-Oghaz H, Veeturi SS, Poppenberg KE, Waqas M, Mandelbaum M, Liaw N, Siddiqui AH, Meng H, Kolega J: Endogenous animal models of intracranial aneurysm development: a review. Neurosurg Rev 2021 Jan 26. Online ahead of print. PMID: 33501561. https://doi.org/10.1007/s10143-021-01481-w
- Poppenberg KE, Li L, Waqas M, Paliwal P, Jiang K, Jarvis JN, Sun Y, Snyder KV, Levy EI, Siddiqui AH, Kolega J, Meng H, Tutino VM: Whole blood transcriptome biomarkers of unruptured intracranial aneurysm. PLoS One 2020 Nov 6;15(11):e0241838. PMID: 33156839. PMCID: PMC7647097 https://doi.org/10.1371/journal.pone.0241838
- Rajabzadeh-Oghaz H, Waqas M, Veeturi SV, Vakharia K, Tso MK, Kenneth SV, Davies JM, Siddiqui AH, Levy EI, Meng H: A Data-Driven Model to Identify High-Risk Aneurysms and Guide Management Decisions: Rupture Resemblance Score. J Neurosurg 2020 Sep 4;1-8. PMID: 32886911. https://doi.org/10.3171/2020.5.JNS193264
- Asgharzadeh H, Shahmohammadi A, Varble N, Levy EI, Meng H, Borazjani I: A Simple Flow Classification Parameter Can Discriminate Rupture Status in Intracranial Aneurysms, Neurosurgery 2020 Oct 15;87(5):E557-E564. PMID: 32421804. PMCID: PMC7566542. https://doi.org/10.1093/neuros/nyaa189
- Rajabzadeh-Oghaz H, van Ooij P, Veeturi SS, Tutino VM, Zwanenburg JJM, Meng H: Inter-patient variations in flow boundary conditions at middle cerebral artery from 7T PC-MRI and influence on Computational Fluid Dynamics of intracranial aneurysms, Computers in Biology and Medicine 2020 May;120:103759. PMID 103759. https://doi.org/10.1016/j.compbiomed.2020.103759
- Hackenberg KAM, Rajabzadeh-Oghaz H, Dreier R, Buchholz BA, Navid A, Rocke DM, Abdulazim A, Hänggi D, Siddiqui A, Macdonald RL, Meng H, Etminan N: Collagen Turnover in Relation to Risk Factors and Hemodynamics in Human Intracranial Aneurysms. Stroke 2020 May;51(5):1624-1628. (epub March 20, 2020). PMID 32188367. http://doi.org/10.1161/STROKEAHA.120.029335
- Waqas M, Chin F, Rajabzadeh-Oghaz H, Gong AD, Rai HH, Mokin M, Vakharia K, Dossani RH, Meng H, Snyder KV, Davies JM, Levy EI, Siddiqui AH: Size of Ruptured Intracranial Aneurysms: A Systematic Review and Meta-analysis. Acta Neurochir 2020 Jun;162(6):1353-1362. http://doi.org/10.1007/s00701-020-04291-z
- Lamooki SR, Tutino VM, Paliwal N, Damiano RJ, Waqas M, Nagesh SSV, Rajabzadeh-Oghaz H, Vakharia K, Siddiqui AH, Meng H: Evaluation of Two Fast Virtual Stenting Algorithms for Intracranial Aneurysm Flow Diversion. Curr Neurovasc Res 2020;17(1):58-70. (epub January 20, 2020). PMID: 31987021. http://doi.org/10.2174/1567202617666200120141608
- Damiano RJ, Tutino VM, Paliwal N, Patel TR, Waqas M, Levy EI, Davies JM, Siddiqui AH, Meng H: Aneurysm characteristics, coil packing, and post-coiling hemodynamics affect long-term treatment outcome. J Neurointerv Surg 2020;12:706–713. PMID: 31848217. PMCID: PMC7293941. http://doi.org/10.1136/neurintsurg-2019-015422. [Epub Dec 17, 2019]
- Maragkos GA, Dmytriw AA, Salem MM, Tutino VM, Meng H, Cognard C, Machi P, Krings T, Mendes Pereira V: Overview of Different Flow Diverters and Flow Dynamics. Neurosurgery. 2020 Jan 1;86. PMID: 31838536. http://doi.org/10.1093/neuros/nyz323
- Damiano RJ, Tutino VM, Lamooki SR, Paliwal N, Davies JM, Siddiqui AH, Meng H: Improving accuracy for finite element modeling of endovascular coiling of intracranial aneurysm, PLoS ONE, 2019 Dec 27;14(12):e0226421. PMID: 31881029. PMCID: PMC6934293. http://doi.org/10.1371/journal.pone.0226421.
- Poppenberg KE, Jiang K, Li L, Sun Y, Meng H, Wallace CA, Hennon T, Jarvis JN: The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches. Arthritis Res Ther. 2019 Nov 9;21(1):230. PMID: 31706344. PMCID: PMC6842535 http://doi.org/10.1186/s13075-019-2010-z.
- Rajabzadeh-Oghaz H, Wang J, Varble N, Sugiyama S-I, Shimizu A, Jing L, Liu J, Yang X, Siddiqui AH, Davies JM, Meng H: Novel Models for Identification of the Ruptured Aneurysm in Patients with Subarachnoid Hemorrhage with Multiple Aneurysms. AJNR Am J Neuroradiol 40 (11) 1939-1946; epub October 24, 2019. PMID 31649161. PMCID: PMC6871507. http://doi.org/10.3174/ajnr.A6259
- Poppenberg KE, Jiang K, Tso MK, Snyder KV, Siddiqui AH, Kolega J, Jarvis JN, Meng H, Tutino VM: Epigenetic Landscapes Suggest that Genetic Risk for Intracranial Aneurysm Operates on the Endothelium. BMC Med Genomics 12(1):149; October 30, 2019. PMID: 31666072. PMCID: PMC6821037. http://doi.org/10.1186/s12920-019-0591-7
- Berg P, Meng H et al: Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)-phase II: rupture risk assessment. Int J Comput Assist Radiol Surg 2019 Oct;14(10):1795-1804. PMID: 31054128. http://doi.org/10.1007/s11548-019-01986-2
- Waqas M, Rajabzadeh-Oghaz H, Tutino VM, Vakharia K, Poppenberg KE, Mowla A, Meng H, Siddiqui AH: Morphologic Parameters and Location Associated with Rupture Status of Intracranial Aneurysms in Elderly Patients. World Neurosurg. 2019 Sep;129:e831-e837. PMID: 31207378 http://doi.org/10.1016/j.wneu.2019.06.045.
- Asgharzadeh H, Asadi H, Meng H, Borazjani I: A non-dimensional parameter for classification of the flow in intracranial aneurysms. II. Patient-specific geometries. Physics of Fluids 2019 Mar;31(3):031905. [Featured Article] PMID: 30967745. PMCID: PMC6436177. http://doi.org/10.1063/1.5081451
- Jiang K, Poppenberg KE, Wong L, Chen Y, Borowitz D, Goetz D, Sheehan D, Frederick C, Tutino VM, Meng H, Jarvis JN: RNA sequencing data from neutrophils of patients with cystic fibrosis reveals potential for developing biomarkers for pulmonary exacerbations. J Cyst Fibros. 2 2019 Mar;18(2):194-202. PMID: 29941318. http://doi.org/10.1016/j.jcf.2018.05.014
- Han X, Sakamoto N, Tomita N, Meng H, Sato M, Ohta M: Influence of TGF-β1 expression in endothelial cells on smooth muscle cell phenotypes and MMP production under shear stress in a co-culture model. Cytotechnology. 2019 Feb 1, 71: 489. PMID: 30707337. http://doi.org/10.1007/s10616-018-0268-7
- Paliwal N, Tutino VM, Shallwani H, Beecher JS, Damiano J, Shakir HJ, Atwal GS, Fennell VS, Natarajan SK, Levy EI, Siddiqui AH, Davies JM, Meng H: Ostium Ratio and Neck Ratio Could Predict the Outcome of Sidewall Intracranial Aneurysms Treated with Flow Diverters. AJNR Am J Neuroradiol. February 2019, 40 (2) 288-294. PMID 306792216. PMCID: PMC6375759. http://doi.org/10.3174/ajnr.A5953
- Tutino VM, Poppenberg KE, Li L, Shallwani H, Jiang K, Jarvis JN, Sun Y, Snyder KV, Levy EI, Siddiqui AH, Kolega J, Meng H: Biomarkers from Circulating Neutrophil Transcriptomes Have Potential To Detect Unruptured Intracranial Aneurysms. J Transl Med. 2018 Dec 28;16(1):373 PMID: 30593281. PMCID: PMC6310942. http://doi.org/10.1186/s12967-018-1749-3
- Paliwal N, Jaiswal P, Tutino VM, Shallwani H, Davies JM, Siddiqui AH, Rai R, Meng H: Outcome prediction of intracranial aneurysm treatment by flow diverters using machine learning. Neurosurg Focus 45 (5):E7, 2018. PMID: 30453461. http://doi.org/10.3171/2018.8.FOCUS18332
- Tutino VM, Poppenberg KE, Li L, Shallwani H, Jiang K, Jarvis JN, Sun Y, Snyder KV, Levy EI, Siddiqui AH, Kolega J, Meng H: Biomarkers from Circulating Neutrophil Transcriptomes Have Potential To Detect Unruptured Intracranial Aneurysms. J Transl Med. 2018 Dec 28;16(1):373 PMID: 30593281. PMCID: PMC6310942. http://doi.org/10.1186/s12967-018-1749-3
- Tutino VM, Poppenberg KE, Jiang K, Jarvis JN, Sun Y, Sonig A, Siddiqui AH, Snyder KV, Levy EI, Kolega J, Meng H: Circulating neutrophil transcriptome may reveal intracranial aneurysm signature. PLoS ONE, 2018 Jan 17;13(1):e0191407. PMID: 29342213. PMCID: PMC5771622. http://doi.org/10.1371/journal.pone.0191407
- Varble N, Tutino VM, Yu J, Sonig A, Siddiqui AH, Davies JM, Meng H: Shared and Distinct Rupture Discriminants of Small and Large Intracranial Aneurysms. Stroke, 49(4):856-864, 2018. PMID: 29535267 PMCID: PMC5871584. http://doi.org/10.1161/STROKEAHA.117.019929
- Paliwal N, Damiano RJ, Varble NA, Tutino VM, Dou Z, Siddiqui AH, Meng H: Methodology for CFD Validation for Medical Use: Application to Intracranial Aneurysm. J Biomech Eng. 2017 Dec 1;139(12). PMID: 28857116. PMCID: PMC5686786. http://doi.org/10.1115/1.4037792
- Damiano RJ, Ma D, Xiang J, Snyder KV, Siddiqui AH, Meng H: Finite Element Modeling of Endovascular Intervention Enables Hemodynamic Prediction of Complex Treatment Strategies of Coiling and Flow Diversion. J Biomech. 2015: 48, 3332–3340. PMID: 26169778. PMCID: PMC4801175. http://doi.org/10.1016/j.jbiomech.2015.06.018
- Xiang J, Tutino VM, Snyder KV, Meng H: CFD: Computational Fluid Dynamics or Confounding Factor Dissemination? The Role of Hemodynamics in Intracranial Aneurysm Rupture Risk Assessment. AJNR Am J Neuroradiol. 2014 Oct;35(10):1849-57. PMID: 24029393. http://doi.org/10.3174/ajnr.A3710
- Meng H, Tutino VM, Xiang J, Siddiqui AH: High WSS or Low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: Toward a unifying hypothesis. AJNR Am J Neuroradiol 2014 Jul;35(7):1254-62. PMID: 23598838. http://doi.org/10.3174/ajnr.A3558
- Bragg AD, Hammond AL, Dhariwal R, Meng H: Hydrodynamic interactions and extreme particle clustering in turbulence. J Fluid Mech (2022) 933:A31. https://doi.org/10.1017/jfm.2021.1099
- Hammond AL, Meng H: Particle Radial Distribution Function and Relative Velocity Measurement in Turbulence at Small Particle-Pair Separations. J Fluid Mech (2021) 921:25. https://doi.org/10.1017/jfm.2021.486
- Hammond AL, Liang Z, Meng H: Holographic deflection imaging measurement of electric charge on aerosol particles. Exp Fluids (2019) 60:103. http://doi.org/10.1007/s00348-019-2744-z
- Dou Z, Bragg AD, Hammond AL, Liang Z, Collins L, Meng H: Effects of Reynolds Number and Stokes Number on Particle-pair Relative Velocity in Isotropic Turbulence: A Systematic Experimental Study, J. Fluid Mech. (2018) 839: 271–292. http://doi.org/10.1017/jfm.2017.813
- Dou Z, Ireland PJ, Bragg AD, Liang Z, Collins L, Meng H: Particle-Pair Relative Velocity Measurement in High-Reynolds-Number Homogeneous and Isotropic Turbulence Using 4-Frame Particle Tracking Velocimetry, Exp. Fluids, (2018) 59:30. http://doi.org/10.1007/s00348-017-2481-0
- Dou Z, Pecenak ZK, Cao L, Woodward SH, Liang Z, Meng H: PIV Measurement of High-Reynolds-Number Homogeneous and Isotropic Turbulence in an Enclosed Flow Apparatus with Fan Agitation, Measurement Science and Technology, 27(3): 35305-35305, 2016. http://doi.org/10.1088/0957-0233/27/3/035305
- de Jong J, Salazar J, Woodward SH, Collins LR, Meng H: Measurement of inertial particle clustering and relative velocity statistics in isotropic turbulence using holographic imaging, Int J Multiphase Flow, 36:324-332, 2010. http://doi.org/10.1016/j.ijmultiphaseflow.2009.11.008
- de Jong J, Woodward SH, Cao L, Salazar J, Collins LR, Meng H: Dissipation rate estimation from PIV in zero-mean isotropic turbulence. Exp. Fluids, 46:499-515, 2009. http://doi.org/10.1007/s00348-008-0576-3
- Salazar J, de Jong J, Cao L, Woodward S, Meng H, Collins L: Experimental and numerical investigation of inertial particle clustering in isotropic turbulence. J. Fluid Mech. 600: 245-256, 2008. http://doi.org/10.1017/S0022112008000372