Susan Zonglu Hua
PhD
Research Interests
Cellular mechanosensitivity; cell-cell and cell-ECM interaction; traumatic brain injury (TBI); microfluidic devices and live-cell imaging
Selected Publications
- Jetta, D., Gottlieb, P. A., Verma, D., Sachs, F. & Hua, S. Z. Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells. Journal of cell science 132, 226076 (2019). DOI: https://doi.org/10.1242/jcs.226076
- Maneshi, M. M., Ziegler, L., Sachs, F., Hua, S. Z. & Gottlieb, P. A. Enantiomeric Abeta peptides inhibit the fluid shear stress response of PIEZO1. Scientific Reports 8, 14267,(2018). DOI: 10.1038/s41598-018-32572-2
- Suffoletto, K., Jetta, D. & Hua, S. Z. E-cadherin mediated lateral interactions between neighbor cells necessary for collective migration. Journal of biomechanics 71, 159-166,(2018). DOI: 10.1016/j.jbiomech.2018.02.002
- Maneshi, M. M., Sachs, F. & Hua, S. Z. Heterogeneous Cytoskeletal Force Distribution Delineates the Onset Ca(2+) Influx Under Fluid Shear Stress in Astrocytes. Frontiers in cellular neuroscience 12, 69,(2018). DOI: https://doi.org/10.3389/fncel.2018.00069
- Maneshi, M. M., Maki, B., Gnanasambandam, R., Belin, S., Popescu, G. K., Sachs, F. & Hua, S. Z. Mechanical stress activates NMDA receptors in the absence of agonists. Scientific Reports 7, 39610,(2017). DOI: 10.1038/srep39610
- Verma, D., Bajpai, V. K., Ye, N., Maneshi, M. M., Jetta, D., Andreadis, S. T., Sachs, F. & Hua, S. Z. Flow induced adherens junction remodeling driven by cytoskeletal forces. Experimental cell research 359, 327-336,(2017). DOI: https://doi.org/10.1016/j.yexcr.2017.08.009
- Maneshi, M. M., Gottlieb, P. A. & Hua, S. Z. A Microfluidic Approach for Studying Piezo Channels. Curr Top Membr 79, 309-334,(2017). DOI: 10.1016/bs.ctm.2016.11.005