Novel techniques for advanced MRI instrumentation; multi-modal biomedical imaging; novel MR imaging formation technology; MR imaging at high and ultrahigh fields; novel device and method development for structural, functional and metabolic imaging using proton and heteronuclear MRI; parallel imaging and compressed sensing based fast imaging methodology; new hardware technology for MR imaging, microimaging, cancer imaging, fetal and neonatal imaging; interventional MRI; PET-MRI in health and cancerous conditions; technical development of high intensity focused ultrasound (HIFU) or magnetic resonance guided focused ultrasound (MRgFUS) in small animal models and humans