Pedro Lei

PhD

Pedro Lei

PhD

Pedro Lei

PhD

Research Topics

Gene delivery; stem cells; tissue engineering; biomaterial

Contact Information

910 Furnas Hall

Buffalo NY, 14260

Phone: (716) 645-1203

Fax: (716) 645-3822

pedrolei@buffalo.edu

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Publications

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  • V. K. Bajpai, L. Kerosuo, G. Tseropoulos, K. A. Cummings, X. Y. Wang, P. Lei, B. Liu, S. Liu, G. K. Popescu, M. E. Bronner, S. T. Andreadis, “Reprogramming Postnatal Human Epidermal Keratinocytes Toward Functional Neural Crest Fates”, Stem Cells 35, 1402-1415 (2017). link PDF
  • P. Mistriotis, V. K. Bajpai, X. Y. Wang, N. Rong, A. Shahini, M. Asmani, M. S. Liang, J. M. Wang, P. Lei, S. Liu, R. G. Zhao, S. T. Andreadis, “NANOG Reverses the Myogenic Differentiation Potential of Senescent Stem Cells by Restoring ACTIN Filamentous Organization and SRF-Dependent Gene Expression”, Stem Cells 35, 207-221 (2017). link
  • N. Likhite, C. A. Jackson, M. S. Liang, M. C. Krzyzanowski, P. Lei, J. F. Wood, B. Birkaya, K. L. Michaels, S. T. Andreadis, S. D. Clark, M. C. Yu, D. M. Ferkey, “The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling”, Sci. Signal. 8, ra115 (2015). link
  • J. Moharil, P. Lei, J. Tian, D. P. Gaile, S. T. Andreadis, “Lentivirus Live Cell Array for Quantitative Assessment of Gene and Pathway Activation during Myogenic Differentiation of Mesenchymal Stem Cells”, PLoS One 10, e0141365 (2015). link
  • C. L. M. Maruyama, N. J. Leigh, J. W. Nelson, A. D. Mccall, R. E. Mellas, P. Lei, T. Andreadis, O. J. Baker, “Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters”, J. Dent. Res. 94, 1610-1617 (2015). link
  • S. Son, M. S. Liang, P. Lei, X. Z. Xue, E. P. Furlani, S. T. Andreadis, “Magnetofection Mediated Transient NANOG Overexpression Enhances Proliferation and Myogenic Differentiation of Human Hair Follicle Derived Mesenchymal Stem Cells”, Bioconjugate Chem. 26, 1314-1327 (2015). link
  • S. Alimperti, P. Lei, Y. Wen, J. Tian, A. M. Campbell, S. T. Andreadis, “Serum-Free Spheroid Suspension Culture Maintains Mesenchymal Stem Cell Proliferation and Differentiation Potential”, Biotechnol. Prog. 30, 974-983 (2014). link
  • R. Padmashali, H. You, N. Karnik, P. Lei, S. T. Andreadis, “Adherens Junction Formation Inhibits Lentivirus Entry and Gene Transfer”, PLoS One 8, e79265 (2013). link
  • A. D. Mccall, J. W. Nelson, N. J. Leigh, M. E. Duffey, P. Lei, S. T. Andreadis, O. J. Baker, “Growth Factors Polymerized Within Fibrin Hydrogel Promote Amylase Production in Parotid Cells”, Tissue Eng. Part A 19, 2215-2225 (2013). link
  • M. S. Liang, M. Koobatian, P. Lei, D. D. Swartz, S. T. Andreadis, “Differential and synergistic effects of mechanical stimulation and growth factor presentation on vascular wall function”, Biomaterials 34, 7281-7291 (2013). link
  • H. You, R. M. Padmashali, A. Ranganathan, P. Lei, N. Girnius, R. J. Davis, S. T. Andreadis, “JNK regulates compliance-induced adherens junctions formation in epithelial cells and tissues”, J. Cell Sci. 126, 2718-2729 (2013). link
  • S. Alimperti, P. Lei, J. Tian, S. T. Andreadis, “A novel lentivirus for quantitative assessment of gene knockdown in stem cell differentiation”, Gene Ther. 19, 1123-1132 (2012). link
  • J. H. Han, P. Mistriotis, P. Lei, D. Wang, S. Liu, S. T. Andreadis, “Nanog Reverses the Effects of Organismal Aging on Mesenchymal Stem Cell Proliferation and Myogenic Differentiation Potential”, Stem Cells 30, 2746-2759 (2012). link
  • J. Wang, P. Lei, S. T. Andreadis, T. J. Mountziaris, “DETECTION OF DNA HYBRIDIZATION VIA FLUORESCENCE INTENSITY VARIATIONS OF ZnSe-DNA QUANTUM DOT BIOSENSORS”, Anal. Lett. 45, 227-241 (2012). link
  • L. M. Lugo, P. Lei, S. T. Andreadis, “Vascularization of the Dermal Support Enhances Wound Re-Epithelialization by In Situ Delivery of Epidermal Keratinocytes”, Tissue Eng. Part A 17, 665-675 (2011). link
  • J. Tian, S. Alimperti, P. Lei, S. T. Andreadis, “Lentiviral microarrays for real-time monitoring of gene expression dynamics”, Lab Chip 10, 1967-1975 (2010). link
  • S. D. Raut, P. Lei, R. M. Padmashali, S. T. Andreadis, “Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays”, J. Control. Release 144, 213-220 (2010). link
  • P. Lei, R. M. Padmashali, S. T. Andreadis, “Cell-controlled and spatially arrayed gene delivery from fibrin hydrogels”, Biomaterials 30, 3790-3799 (2009). link
  • R. Singh, P. Lei, S. T. Andreadis, “PKC-delta binds to E-cadherin and mediates EGF-induced cell scattering”, Exp. Cell Res. 315, 2899-2913 (2009). link
  • J. Tian, P. Lei, S. G. Laychock, S. T. Andreadis, “Regulated insulin delivery from human epidermal cells reverses hyperglycemia”, Mol. Ther. 16, 1146-1153 (2008). link
  • K. G. Cornwell, P. Lei, S. T. Andreadis, G. D. Pins, “Crosslinking of discrete self-assembled collagen threads: Effects on mechanical strength and cell-matrix interactions”, J. Biomed. Mater. Res. Part A 80A, 362-371 (2007). link
  • P. Lei, A. Ogunade, K. L. Kirkwood, S. G. Laychock, S. T. Andreadis, “Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: Implications for treatment of diabetes”, Tissue Eng. 13, 2119-2131 (2007). link
  • B. G. Bajaj, P. Lei, S. T. Andreadis, “Efficient gene transfer to human epidermal keratinocytes on fibronectin: In vitro evidence for transduction of epidermal stem cells”, Mol. Ther. 11, 969-979 (2005). link
  • P. Lei, S. T. Andreadis, “Stoichiometric limitations in assembly of active recombinant retrovirus”, Biotechnol. Bioeng. 90, 781-792 (2005). link
  • P. Lei, B. Bajaj, S. T. Andreadis, “Retrovirus-associated heparan sulfate mediates immobilization and gene transfer on recombinant fibronectin”, J. Virol. 76, 8722-8728 (2002). link
  • P. Lei, B. Bajaj, S. T. Andreadis, “Retrovirus-associated heparan sulfate mediates immobilization and gene transfer on recombinant fibronectin (vol 76, pg 8722, 2002)”, J. Virol. 76, 11176-11176 (2002). link
  • B. Bajaj, P. Lei, S. T. Andreadis, “High efficiencies of gene transfer with immobilized recombinant retrovirus: Kinetics and optimization”, Biotechnol. Prog. 17, 587-596 (2001). link

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