Engineering a Healthier Future
Ashlee N. Ford Versypt
PhD
Research Topics
computational science and engineering; applied mathematics; mathematical biology; multiscale modeling; physiology; pharmacology; toxicology; kidney; bone; cancer; lung; pharmacokinetics; immunotherapy; drug delivery; tissue damage; porous materials; extracellular matrix; kinetics; transport; numerical methods
Books
- A. N. Ford Versypt, R. A. Segal, and S. S. Sindi, editors, Mathematical Modeling for Women’s Health, The IMA Volumes in Mathematics and its Applications, Springer, Cham, Switzerland, 2024. DOI: https://doi.org/10.1007/978-3-031-58516-6.
- R. D. Braatz, A. N. Ford Versypt, L. M. Goh, and U. Ravaioli, Nanoscale Drug Delivery Module: Student’s Edition, Materials World Modules, Northwestern University, Evanston, IL, 2012.
- R. D. Braatz, A. N. Ford Versypt, L. M. Goh, and U. Ravaioli, Nanoscale Drug Delivery Module: Teacher’s Edition, Materials World Modules, Northwestern University, Evanston, IL, 2012.
Peer-Reviewed Journal Publications
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- H. Y. Thomas, A. N. Ford Versypt, “A mathematical model of glomerular fibrosis in diabetic kidney disease to predict therapeutic efficacy”, Front. Pharmacol. 15, 1481768 (2024).
- A. N. Ford Versypt, R. A. Segal, S. S. Sindi, “Collaborative Workshop for Women in Mathematical Biology: Mathematical Modeling for Women’s Health”, Applications of Dynamical Systems in Biology and Medicine , 1-7 (2024).
- C. V. Cook, A. M. Lighty, B. J. Smith, A. N. Ford Versypt, “A Review of Mathematical Modeling of Bone Remodeling from a Systems Biology Perspective”, Front. Syst. Biol. 4, 1368555 (2024).
- P. Islam, J. A. Ice, S. E. Alake, P. Adedigba, B. Hatter, K. Robinson, S. L. Clarke, A. N. Ford Versypt, J. Ritchey, E. A. Lucas, B. J. Smith, “Fructooligosaccharides act on the gut–bone axis to improve bone independent of Tregs and alter osteocytes in young adult C57BL/6 female mice”, JBMR Plus 8, ziae021 (2024).
- K. Patidar, J. H. Deng, C. S. Mitchell, A. N. Ford Versypt, “Cross-Domain Text Mining of Pathophysiological Processes Associated with Diabetic Kidney Disease”, Int. J. Mol. Sci. 25, 4503 (2024).
- M. A. Islam, M. Getz, P. Macklin, A. N. Ford Versypt, “An agent-based modeling approach for lung fibrosis in response to COVID-19”, PLoS Comput. Biol. 19, e1011741 (2023).
- B. A. Bartlett, Y. Feng, C. A. Fromen, A. N. Ford Versypt, “Computational fluid dynamics modeling of aerosol particle transport through lung airway mucosa”, Comput. Chem. Eng. 179, 108458 (2023).
- S. R. Peyton, L. W. Chow, S. D. Finley, A. N. Ford Versypt, R. Hill, M. L. Kemp, E. M. Langer, A. P. McGuigan, A. S. Meyer, S. K. Seidlits, K. Roy, S. M. Mumenthaler, “Synthetic living materials in cancer biology”, Nature Reviews Bioengineering 1, NA (2023).
- E. A. Chacin Ruiz, K. E. Swindle-Reilly, A. N. Ford Versypt, “Experimental and mathematical approaches for drug delivery for the treatment of wet age-related macular degeneration”, J. Control. Release 363, 464-483 (2023).
- C. V. Cook, M. A. Islam, B. J. Smith, A. N. Ford Versypt, “Mathematical modeling of the effects of Wnt‐10b on bone metabolism”, AIChE J. 68, e17809 (2022).
- H. Y. Thomas, A. N. Ford Versypt, “Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation”, J. Biol. Eng. 16, 19 (2022).
- M. W. Liberatore, D. Lepek, L. Ford, T. Carter, J. Pascal, M. Lamm, C. Patton Luks, D. L. Silverstein, A. N. Ford Versypt, S. Butler Velegol, T. Vogel, N. Raikar, M. Kipper, C. W. West, “AIChE Virtual Communities of Practice – Supporting Faculty During the COVID-19 Pandemic”, Chem. Eng. Educ. 56, 68-78 (2022).
- M. A. Islam, C. V. Cook, B. J. Smith, A. N. Ford Versypt, “Mathematical Modeling of the Gut-Bone Axis and Implications of Butyrate Treatment on Osteoimmunology”, Ind. Eng. Chem. Res. 60, 17814-17825 (2021). PDF link
- A. N. Ford Versypt, “Multiscale Modeling in Disease”, Curr. Opin. Syst. Biol. 27, 100340 (2021).
- J. E. Bara, A. N. Ford Versypt, R. B. Getman, C. A. Kieslich, R. S. Voronov, "Apps for chemical engineering education: off the shelf and do it yourself development options", Chem. Eng. Educ. 54, 137-142 (2020). PDF link
- C. V. Eastep, G. K. Harrell, A. N. McPeak, A. N. Ford Versypt, "A MATLAB app to introduce chemical engineering design concepts to engineering freshmen through a pharmaceutical dosing case study", Chem. Eng. Educ. 53, 85-90 (2019). PDF
- A. N. Ford Versypt, "Self-evaluation and reflection for professional development of chemical engineering students", Chem. Eng. Educ. 53, 157-161 (2019). PDF
- S. M. Ruggiero, A. N. Ford Versypt, “SBMLtoODEpy: A software program for converting SBML models into ODE models in Python”, J. Open Source Software 4, 1643 (2019).
- M. R. Pilvankar, H. L. Yong, A. N. Ford Versypt, “A glucose-dependent pharmacokinetic/pharmacodynamic model of ACE inhibition in kidney cells”, Processes 7, 131 (2019).
- J. D. Crall, B. L. de Bivort, B. Dey, A. N. Ford Versypt, “Social buffering of pesticides in bumblebees: Agent-based modeling of the effects of colony size and neonicotinoid exposure on behavior within nests”, Front. Ecol. Evol. 7, 51 (2019).
- Y. T. Nguyen Edalgo, A. L. Zornes, A. N. Ford Versypt, “A hybrid discrete-continuous model of metastatic cancer cell migration through a remodeling extracellular matrix”, AIChE J. 65, e16671 (2019).
- S. M. Ruggiero, J. Zhao, A. N. Ford Versypt, “Building a MATLAB graphical user interface to solve ordinary differential equations as a final project for an interdisciplinary elective course on numerical computing”, J. Comput. Sci. Educ. 9, 19-28 (2018).
- A. N. Ford Versypt, J. D. Crall, B. Dey, “BeeNestABM: An open-source agent-based model of spatiotemporal distribution of bumblebees in nests”, J. Open Source Software 3, 718 (2018).
- S. A. Irfan, R. Razali, K. KuShaari, N. Mansor, B. Azeem, A. N. Ford Versypt, “A review of mathematical modeling and simulation of controlled-release fertilizers”, J. Control. Release 271, 45-54 (2018).
- M. R. Pilvankar, M. A. Higgins, A. N. Ford Versypt, “Mathematical model for glucose dependence of the local renin-angiotensin system in podocytes”, Bull. Math. Biol. 80, 880-905 (2018).
- Y. T. Nguyen Edalgo, A. N. Ford Versypt, “Mathematical modeling of metastatic cancer migration through a remodeling extracellular matrix”, Processes 6, 58 (2018).
- J. D. Crall, C. M. Switzer, R. L. Oppenheimer, A. N. Ford Versypt, B. Dey, A. Brown, M. Eyster, C. Guerin, N. E. Pierce, S. A. Combes, B. L. de Bivort, “Neonicotinoid exposure disrupts bumblebee nest behavior, social networks, and thermoregulation”, Science 362, 683-686 (2018).
- A. N. Ford Versypt, "Choose your own kinetics adventure: student-designed case studies for chemical reaction engineering course projects", Transactions on techniques in STEM education 3, 48-56 (2017). PDF
- A. N. Ford Versypt, G. K. Harrell, A. N. McPeak, “ACEInhibPKPD: An open-source MATLAB app for a pharmacokinetic/pharmacodynamic model of ACE inhibition”, J. Open Source Software 2, 340 (2017).
- A. N. Ford Versypt, G. K. Harrell, A. N. McPeak, “A pharmacokinetic/pharmacodynamic model of ACE inhibition of the renin-angiotensin system for normal and impaired renal function”, Comput. Chem. Eng. 104, 311-322 (2017).
- S. M. Ruggiero, M. R. Pilvankar, A. N. Ford Versypt, “Mathematical modeling of tuberculosis granuloma activation”, Processes 5, 79 (2017).
- J. C. Arciero, L. Ellwein, A. N. Ford Versypt, E. Makrides, A. T. Layton, “Modeling blood flow control in the kidney”, Applications of Dynamical Systems in Biology and Medicine 158, 55-73 (2015).
- A. N. Ford Versypt, E. Makrides, J. C. Arciero, L. Ellwein, A. T. Layton, “Bifurcation study of blood flow control in the kidney”, Math. Biosci. 263, 169-179 (2015).
- A. N. Ford Versypt, P. D. Arendt, D. W. Pack, R. D. Braatz, “Derivation of an analytical solution to a reaction-diffusion model for autocatalytic degradation and erosion in polymer microspheres”, PLoS One 10, e0135506 (2015).
- A. Mesbah, A. N. Ford Versypt, X. Zhu, R. D. Braatz, “Nonlinear model-based control of thin-film drying for continuous pharmaceutical manufacturing”, Ind. Eng. Chem. Res. 53, 7447-7460 (2014).
- A. N. Ford Versypt, R. D. Braatz, “Analysis of finite difference discretization schemes for diffusion in spheres with variable diffusivity”, Comput. Chem. Eng. 71, 241-252 (2014).
- A. N. Ford Versypt, D. W. Pack, R. D. Braatz, “Mathematical modeling of drug delivery from autocatalytically degradable PLGA microspheres -- A review”, J. Control. Release 165, 29-37 (2013).
- M. Kishida, A. N. Ford Versypt, D. W. Pack, R. D. Braatz, “Optimal control of one-dimensional cellular uptake in tissue engineering”, Optim. Control Appl. Methods 34, 680-695 (2013).
- M. Jiang, M. H. Wong, Z. Zhu, J. Q. Zhang, L. F. Zhou, K. Wang, A. N. Ford Versypt, T. Si, L. M. Hasenberg, Y.-E. Li, R. D. Braatz, “Towards achieving a flattop crystal size distribution by continuous seeding and controlled growth”, Chem. Eng. Sci. 77, 2-9 (2012).
- A. N. Ford, D. V. Papavassiliou, “Flow around surface-attached carbon nanotubes”, Ind. Eng. Chem. Res. 45, 1797-1804 (2006).
Peer-Reviewed Conference Proceedings
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- A. N. Ford Versypt, C. V. Cook, A. N. Johns, “Interactive Coding Templates for Courses and Undergraduate Research Using MATLAB Live Scripts”, Computer Aided Chemical Engineering , 3499-3504 (2024). PDF
- A. N. Ford Versypt, J. E. Errington, D. A. Kofke, M. Sepesy, M. T. Swihart, "A Departmental Research Methods Course to Support New Undergraduate Researchers", ASEE Annual Conference & Exposition , NA (2024). PDF
- A. N. Johns, R. P. Hesketh, M. D. Stuber, A. N. Ford Versypt, "Numerical Problem Solving across the Curriculum with Python and MATLAB Using Interactive Coding Templates: A Workshop for Chemical Engineering Faculty", ASEE Annual Conference & Exposition , NA (2023). PDF
- H. Y. Thomas, A. N. Ford Versypt, “Collagen Deposition in Diabetic Kidney Disease Boosts Intercellular Signaling: A Mathematical Model”, IFAC PAPERSONLINE 55, 68-73 (2022).
- A. N. Ford Versypt, S. L. Carpenter, T. L. Adkins II, T. A. Sperry, Y. Feng, "Kidney and Lung Demonstrations to Introduce Engineering Concepts to Middle School Students and Their Grandparents", ASEE Annual Conference & Exposition , NA (2021). PDF
- A. N. Ford Versypt, D. Khvostichenko, “Clean water through chemical engineering: Introducing K-12 students to ChE using filtration”, ASEE Annual Conference & Exposition (2020).
- A. N. Ford Versypt, J. J. Versypt, H. Gappa-Fahlenkamp, “University-led engineering outreach to adults: public engagement and senior adult initiatives”, Proceedings of the ASEE Midwest Section Conference (2019).
- A. N. Ford Versypt, “An interdisciplinary elective course to build computational skills for mathematical modeling in science and engineering”, ASEE Annual Conference & Exposition (2019).
- A. N. Ford Versypt, "Choose Your Own Kinetics Adventure: Student-Designed Case Studies for Chemical Reaction Engineering Course Projects", Proceedings of the ASEE Midwest Section Conference , NA (2017). PDF
- A. N. Ford Versypt, “Self-reflection assignments for evaluating non-technical skills and setting goals for professional development”, ASEE Annual Conference & Exposition (2017).
- G. K. Harrell, A. N. McPeak, A. N. Ford Versypt, “A pharmacokinetic simulation-based module to introduce mass balances and chemical engineering design concepts to engineering freshmen”, ASEE Annual Conference & Exposition (2017).
- A. E. Lu, J. A. Paulson, N. J. Mozdzierz, A. Stockdale, A. N. Ford Versypt, K. R. Love, J. C. Love, R. D. Braatz, “Control systems technology in the advanced manufacturing of biologic drugs”, IEEE International Conference on Control Applications , 1505-1515 (2015).
- J. J. Versypt, A. N. Ford Versypt, “Mapping rural students’ STEM involvement: Case studies of chemical engineering undergraduate enrollment in the states of Illinois and Kansas”, ASEE Annual Conference & Exposition (2013).
- A. N. Ford, D. W. Pack, R. D. Braatz, “Multi-scale modeling of PLGA microparticle drug delivery systems”, Computer Aided Chemical Engineering 29, 1475-1479 (2011).
- M. Kishida, A. N. Ford, D. W. Pack, R. D. Braatz, “Optimal control of cellular uptake in tissue engineering”, American Control Conference , 2118-2123 (2008).