Our Biochemical and Biomedical Engineering faculty and students focus on tissue replacement and regeneration.
By studying the role of mechanical forces on cell behavior, protein glycosylation, stem cell aging, and stem cell differentiation, they develop novel technologies such as production of value-added chemicals, engineering novel proteins with improved properties, development of anti-clotting agents, scale-up production of stem cells for cell therapies and engineering tissues such as blood vessels, skin, bone, and cartilage.
Research Topics
Stem cells for vascular tissue engineering; signaling pathways in cell-cell adhesion and wound healing; lentiviral vectors and lentiviral microarrays for high-throughput gene expression analysis and gene discovery
Research Topics
Computational science and engineering; applied mathematics; mathematical biology; multiscale modeling; physiology; pharmacology; toxicology; kidney; bone; cancer; lung; pharmacokinetics; immunotherapy; drug delivery; tissue damage; porous materials; extracellular matrix; kinetics; transport; numerical methods
Research Topics
Expertise: systems biology, bioinformatics, computational biology, mathematical modeling, systems analysis, design of experiments, network inference, process optimization. Applications: biopharmaceutical manufacturing, drug discovery & repurposing, systems pharmacology, monoclonal antibody, protein glycosylation, biogerontology, mitochondrial DNA, programmed cell death, circadian rhythms, stem cell differentiation
Research Topics
Gene delivery; stem cells; tissue engineering; biomaterial
Research Topics
Molecular dynamics simulation; computational biophysics; statistical thermodynamics; lipid membrane modeling; protein-lipid interactions
Research Topics
Bioengineering; Systems Biology; Glycosciences; Cell and Molecular Engineering; Human diseases
Research Topics
Transport phenomena; bioactive surfaces; biological pores; transdermal transport
Research Topics
Liver stem cell biology; differentiation; cell therapy; organogenesis; disease modeling; tissue engineering; multimodality molecular imaging; monitoring molecular events in living subjects
Research Topics
Protein engineering; Yeast surface display; Bioinformatics; Molecular Dynamics Simulations
Research Topics
Metabolic Engineering; Heterologous Natural Product Biosynthesis; Vaccine Design and Delivery
