Schematic of Hybrid Delivery Vector
The Pfeifer research group has designed multiple vehicles for vaccine delivery to enhance the final immune response. These delivery devices have included microbial cells engineered to trigger a strong and directed immune response.
This project is linked to a theme within our group focused upon vaccine delivery and design. Long-term goals include effective and cost-effective vaccine production for broad distribution. In this work, we have designed a hybrid delivery vector composed of two components: a cationic polymer (termed a poly (beta-amino ester)) and an E. coli cell (capable of packaging diverse antigen content). The project cross-sects materials, biotech, medicine, and engineering.