Chong Cheng

PhD

Chong Cheng

PhD

Chong Cheng

PhD

Research Topics

Biodegradable functional polymers and nanostructures, new drug delivery systems, synthetic materials for tissue engineering.

Contact Information

312 Furnas Hall

Buffalo NY, 14260

Phone: (716) 645-1193

Fax: (716) 645-3822

ccheng8@buffalo.edu

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Publications

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  • N. Shahkaramipour, S. N. Ramanan, D. Fister, E. Park, S. R. Venna, H. T. Sun, C. Cheng, H. Lin, “Facile Grafting of Zwitterions onto the Membrane Surface To Enhance Antifouling Properties for Wastewater Reuse”, Ind. Eng. Chem. Res. 56, 9202-9212 (2017). link
  • H. T. Sun, I. Yarovoy, M. Capeling, C. Cheng, “Polymers in the Co-delivery of siRNA and Anticancer Drugs for the Treatment of Drug-resistant Cancers”, Top. Curr. Chem. 375, 24 (2017). link
  • S. Shah, J. Y. Liu, S. Ng, S. J. Luo, R. L. Guo, C. Cheng, H. Q. Lin, “Transport properties of small molecules in zwitterionic polymers”, J. Polym. Sci. Pt. B-Polym. Phys. 54, 1924-1934 (2016). link
  • H. T. Sun, C. K. Chen, H. G. Cui, C. Cheng, “Crosslinked polymer nanocapsules”, Polym. Int. 65, 351-361 (2016). link
  • H. Y. Huang, R. Hernandez, J. M. Geng, H. T. Sun, W. T. Song, F. Chen, S. A. Graves, R. J. Nickles, C. Cheng, W. B. Cai, J. F. Lovell, “A porphyrin-PEG polymer with rapid renal clearance”, Biomaterials 76, 25-32 (2016). link
  • J. Zou, Y. Yu, Y. K. Li, W. Ji, C. K. Chen, W. C. Law, P. N. Prasad, C. Cheng, “Well-defined diblock brush polymer-drug conjugates for sustained delivery of paclitaxel”, Biomater. Sci. 3, 1078-1084 (2015). link
  • C. H. Jones, M. F. Chen, A. Gollakota, A. Ravikrishnan, G. J. Zhang, S. Lin, M. Tan, C. Cheng, H. Q. Lin, B. A. Pfeifer, “Structure Function Assessment of Mannosylated Poly(beta-amino esters) upon Targeted Antigen Presenting Cell Gene Delivery”, Biomacromolecules 16, 1534-1541 (2015). link
  • C. H. Jones, C. K. Chen, M. F. Chen, A. Ravikrishnan, H. G. Zhang, A. Gollakota, T. C. Chung, C. Cheng, B. A. Pfeifer, “PEGylated Cationic Polylactides for Hybrid Biosynthetic Gene Delivery”, Mol. Pharm. 12, 846-856 (2015). link
  • Y. Yu, C. K. Chen, W. C. Law, H. Sun, P. N. Prasad, C. Cheng, “A degradable brush polymer-drug conjugate for pH-responsive release of doxorubicin”, Polym. Chem. 6, 953-961 (2015). link
  • Y. K. Li, L. Christian-Tabak, V. L. F. Fuan, J. Zou, C. Cheng, “Crosslinking-Induced Morphology Change of Latex Nanoparticles: A Study of RAFT-Mediated Polymerization in Aqueous Dispersed Media Using Amphiphilic Double-Brush Copolymers as Reactive Surfactants”, J. Polym. Sci. Pol. Chem. 52, 3250-3259 (2014). link
  • Y. Yu, J. Zou, C. Cheng, “Synthesis and biomedical applications of functional poly(alpha-hydroxyl acid)s”, Polym. Chem. 5, 5854-5872 (2014). link
  • G. M. Lin, C. B. Yang, R. Hu, C. K. Chen, W. C. Law, T. Anderson, B. T. Zhang, Q. T. Nguyen, H. T. Toh, H. S. Yoon, C. Cheng, K. T. Yong, “Interleukin-8 gene silencing on pancreatic cancer cells using biodegradable polymer nanoplexes”, Biomater. Sci. 2, 1007-1015 (2014). link
  • C. K. Chen, Q. Wang, C. H. Jones, Y. Yu, H. G. Zhang, W. C. Law, C. K. Lai, Q. H. Zeng, P. N. Prasad, B. A. Pfeifer, C. Cheng, “Synthesis of pH-Responsive Chitosan Nanocapsules for the Controlled Delivery of Doxorubicin”, Langmuir 30, 4111-4119 (2014). link
  • Y. Yu, C. K. Chen, W. C. Law, E. Weinheimer, S. Sengupta, P. N. Prasad, C. Cheng, “Polylactide-graft-doxorubicin Nanoparticles with Precisely Controlled Drug Loading for pH-Triggered Drug Delivery”, Biomacromolecules 15, 524-532 (2014). link
  • Y. J. Fan, M. Hsiung, C. Cheng, E. S. Tzanakakis, “Facile Engineering of Xeno-Free Microcarriers for the Scalable Cultivation of Human Pluripotent Stem Cells in Stirred Suspension”, Tissue Eng. Part A 20, 588-599 (2014). link
  • C. K. Chen, W. C. Law, R. Aalinkeel, Y. Yu, B. Nair, J. C. Wu, S. Mahajan, J. L. Reynolds, Y. K. Li, C. K. Lai, E. S. Tzanakakis, S. A. Schwartz, P. N. Prasad, C. Cheng, “Biodegradable cationic polymeric nanocapsules for overcoming multidrug resistance and enabling drug-gene co-delivery to cancer cells”, Nanoscale 6, 1567-1572 (2014). link
  • G. M. Lin, R. Hu, W. C. Law, C. K. Chen, Y. C. Wang, H. L. Chin, Q. T. Nguyen, C. K. Lai, H. S. Yoon, X. M. Wang, G. X. Xu, L. Ye, C. Cheng, K. T. Yong, “Biodegradable Nanocapsules as siRNA Carriers for Mutant K-Ras Gene Silencing of Human Pancreatic Carcinoma Cells”, Small 9, 2757-2763 (2013). link
  • C. K. Chen, C. H. Jones, P. Mistriotis, Y. Yu, X. N. Ma, A. Ravikrishnan, M. Jiang, S. T. Andreadis, B. A. Pfeifer, C. Cheng, “Poly(ethylene glycol)-block-cationic polylactide nanocomplexes of differing charge density for gene delivery”, Biomaterials 34, 9688-9699 (2013). link
  • C. H. Jones, S. Rane, E. Patt, A. Ravikrishnan, C. K. Chen, C. Cheng, B. A. Pfeifer, “Polymyxin B Treatment Improves Bactofection Efficacy and Reduces Cytotoxicity”, Mol. Pharm. 10, 4301-4308 (2013). link
  • C. H. Jones, C. K. Chen, M. Jiang, L. Fang, C. Cheng, B. A. Pfeifer, “Synthesis of Cationic Polylactides with Tunable Charge Densities as Nanocarriers for Effective Gene Delivery”, Mol. Pharm. 10, 1138-1145 (2013). link
  • Y. Yu, C. K. Chen, W. C. Law, J. Mok, J. Zou, P. N. Prasad, C. Cheng, “Well-Defined Degradable Brush Polymer-Drug Conjugates for Sustained Delivery of Paclitaxel”, Mol. Pharm. 10, 867-874 (2013). link
  • C. K. Chen, W. C. Law, R. Aalinkeel, B. Nair, A. Kopwitthaya, S. D. Mahajan, J. L. Reynolds, J. Zou, S. A. Schwartz, P. N. Prasad, C. Cheng, “Well-Defined Degradable Cationic Polylactide as Nanocarrier for the Delivery of siRNA to Silence Angiogenesis in Prostate Cancer”, Adv. Healthc. Mater. 1, 751-761 (2012). link
  • Y. Li, J. Zou, B. P. Das, M. Tsianou, C. Cheng, “Well-Defined Amphiphilic Double-Brush Copolymers and Their Performance as Emulsion Surfactants”, Macromolecules 45, 4623-4629 (2012). link
  • J. Zou, Y. Yu, L. Yu, Y. Li, C.-K. Chen, C. Cheng, “Well-Defined Drug-Conjugated Biodegradable Nanoparticles by Azide-Alkyne Click Crosslinking in Miniemulsion”, J. Polym. Sci. Pol. Chem. 50, 142-148 (2012). link
  • Y. Li, E. Themistou, J. Zou, B. P. Das, M. Tsianou, C. Cheng, “Facile Synthesis and Visualization of Janus Double-Brush Copolymers”, ACS Macro Lett. 1, 52-56 (2012). link
  • Y. Li, E. Themistou, B. P. Das, L. Christian-Tabak, J. Zou, M. Tsianou, C. Cheng, “Polyelectrolyte Nanocages via Crystallized Miniemulsion Droplets”, Chem. Commun. , 11697-11699 (2011). link
  • J. Zou, C. C. Hew, E. Themistou, Y. Li, C.-K. Chen, P. Alexandridis, C. Cheng, “Clicking Well-Defined Biodegradable Nanoparticles and Nanocapsules by UV-Induced Thiol-Ene Cross-Linking in Transparent Miniemulsions”, Adv. Mater. , 4274-4277 (2011). link
  • J. Zou, G. Jafr, E. Themistou, Y. Yap, Z. A. P. Wintrob, P. Alexandridis, A. C. Ceacareanu, C. Cheng, “pH-Sensitive Brush Polymer-Drug Conjugates by Ring-Opening Metathesis Copolymerization”, Chem. Commun. 47, 4493-4495 (2011). link
  • Y. Yu, J. Zou, L. Yu, W. Jo, Y. K. Li, W. C. Law, C. Cheng, “Functional Polylactide-g-Paclitaxel-Poly(ethylene glycol) by Azide-Alkyne Click Chemistry”, Macromolecules 44, 4793-4800 (2011). link
  • J. Ma, J. W. Bartels, Z. Li, K. Zhang, C. Cheng, K. L. Wooley, “Synthesis and Solution-state Assembly or Bulk State Thiol-ene Crosslinking of Pyrrolidinone- and Alkene-functionalized Amphiphilic Block Fluorocopolymers: From Functional Nanoparticles to Anti-fouling Coatings”, Aust. J. Chem. 63, 1159-1163 (2010). link
  • Z. Li, J. Ma, C. Cheng, K. Zhang, K. L. Wooley, “Synthesis of Hetero-Grafted Amphiphilic Diblock Molecular Brushes and Their Self-Assembly in Aqueous Medium”, Macromolecules 43, 1182-1184 (2010). link
  • C. Cheng, N. L. Yang, “Well-Defined Diblock Macromonomer with a Norbornene Group at Block Junction: Anionic Living Linking Synthesis and Ring-Opening Metathesis Polymerization”, Macromolecules 43, 3153-3155 (2010). link
  • J. Ma, C. Cheng, K. L. Wooley, “The Power of RAFT for Creating Polymers Having Imbedded Side-Chain Functionalities: Norbornenyl-Functionalized Polymers and their Transformations via ROMP and Thiol-ene Reactions”, Aust. J. Chem. 62, 1507-1519 (2009). link
  • G. Sun, H. F. Fang, C. Cheng, P. Lu, K. Zhang, A. V. Walker, J. S. A. Taylor, K. L. Wooley, “Benzaldehyde-Functionalized Polymer Vesicles”, ACS Nano 3, 673-681 (2009). link
  • J. Ma, C. Cheng, K. L. Wooley, “Cycloalkenyl-Functionalized Polymers and Block Copolymers: Syntheses via Selective RAFT Polymerizations and Demonstration of Their Versatile Reactivity”, Macromolecules 42, 1565-1573 (2009). link
  • Z. Li, K. Zhang, J. Ma, C. Cheng, K. L. Wooley, “Facile Syntheses of Cylindrical Molecular Brushes by a Sequential RAFT and ROMP "Grafting-Through" Methodology”, J. Polym. Sci. Pol. Chem. 47, 5557-5563 (2009). link
  • J. Ma, C. Cheng, G. R. Sun, K. L. Wooley, “Well-Defined Polymers Bearing Pendent Alkene Functionalities via Selective RAFT Polymerization”, Macromolecules 41, 9080-9089 (2008). link

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