Expertise: systems biology, bioinformatics, computational biology, mathematical modeling, systems analysis, design of experiments, network inference, process optimization. Applications: biopharmaceutical manufacturing, drug discovery & repurposing, systems pharmacology, monoclonal antibody, protein glycosylation, biogerontology, mitochondrial DNA, programmed cell death, circadian rhythms, stem cell differentiation
302 Furnas Hall
Phone: (716) 645-0952
Dr. Gunawan’s laboratory is engaged in a broad range of activities in the areas of computational systems biology, bioprocess engineering, and bioinformatics. Our primary specializations include mathematical modeling, parameter estimation, systems analysis, bioprocess optimization, and design of experiments. Our research is driven by the mission to create enabling and innovative computational tools, based on rigorous mathematical underpinnings, systems modeling and analysis, and advanced machine learning and optimization algorithms, for the extraction of mechanistic and actionable insights from heterogeneous biological data. Our tools have been applied to give answers to biological questions of biotechnological, biomedical and biopharmaceutical significance. Vignettes of our current research projects are provided below.