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• J. J. León, N. Oetiker, N. Torres, N. Bruna, E. Oskolkov, P. D. Lei, A. N. Kuzmin, K. W. Chen, S. Andreadis, B. A. Pfeifer, M. T. Swihart, P. N. Prasad, J. Pérez-Donoso, “Microbial green synthesis of luminescent terbium sulfide nanoparticles using <i>E. Coli</i>: a rare earth element detoxification mechanism”, Microb. Cell. Fact. 23, 248 (2024). PDF
• A. K. Podder, M. A. Mohamed, R. A. Seidman, G. Tseropoulos, J. J. Polanco, P. Lei, F. J. Sim, S. T. Andreadis, “Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system”, Sci. Adv. 10, eadk9918 (2024).
• S. E. Cassel, B. M. Huntington, W. Chen, P. Lei, S. T. Andreadis, A. M. Kloxin, “Dynamic reporters for probing real-time activation of human fibroblasts from single cells to populations”, APL Bioeng. 8, 026127 (2024).
• D. Choudhury, N. Rong, H. V. S. Kumar, S. Swedick, R. Z. Samuel, P. Mehrotra, J. Toftegaard, N. Rajabian, R. Thiyagarajan, A. K. Podder, Y. L. Wu, S. Shahini, K. L. Seldeen, B. Troen, P. Lei, S. T. Andreadis, “Proline restores mitochondrial function and reverses aging hallmarks in senescent cells”, Cell Reports 43, 113738 (2024).
• K. Nam, H. T. dos Santos, F. Maslow, T. Small, R. Z. Samuel, P. Lei, S. T. Andreadis, O. J. Baker, “Fibrin hydrogels fortified with FGF-7/10 and laminin-1 peptides promote regeneration of irradiated salivary glands”, Acta Biomater. 172, 147-158 (2023).
• Y. Y. Liu, P. Lei, R. Z. Samuel, A. M. Kashyap, T. Groth, W. Bshara, S. Neelamegham, S. T. Andreadis, “Cadherin-11 increases tumor cell proliferation and metastatic potential via Wnt pathway activation”, Mol. Oncol. (2023).
• P. Mehrotra, I. Ikhapoh, P. D. Lei, G. Tseropoulos, Y. L. Zhang, J. M. Wang, S. Liu, M. E. Bronner, S. T. Andreadis, “Wnt/BMP Mediated Metabolic Reprogramming Preserves Multipotency of Neural Crest-Like Stem Cells”, Stem Cells 41, 287-305 (2023).
• D. Choudhury, N. Rong, I. Ikhapoh, N. Rajabian, G. Tseropoulos, Y. L. Wu, P. Mehrotra, R. Thiyagarajan, A. Shahini, K. L. Seldeen, B. R. Troen, P. Lei, S. T. Andreadis, “Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells”, Cell Reports 41, 111744 (2022).
• K. Nam, H. T. dos Santos, F. Maslow, B. G. Trump, P. Lei, S. T. Andreadis, O. J. Baker, “Laminin-1 Peptides Conjugated to Fibrin Hydrogels Promote Salivary Gland Regeneration in Irradiated Mouse Submandibular Glands”, Front. Bioeng. Biotechnol. 9, 729180 (2021).
• A. Shahini, N. Rajabian, D. Choudhury, S. Shahini, K. Vydiam, T. Nguyen, J. Kulczyk, T. Santarelli, I. Ikhapoh, Y. L. Zhang, J. M. Wang, S. Liu, A. Stablewski, R. Thiyagarajan, K. Seldeen, B. R. Troen, J. Peirick, P. Lei, S. T. Andreadis, “Ameliorating the hallmarks of cellular senescence in skeletal muscle myogenic progenitors in vitro and in vivo”, Sci. Adv. 7, eabe5671 (2021).
• H. T. dos Santos, K. Nam, C. T. Brown, S. M. Dean, S. Lewis, C. S. Pfeifer, P. Lei, M. J. Petris, S. T. Andreadis, O. J. Baker, “Trimers Conjugated to Fibrin Hydrogels Promote Salivary Gland Function”, J. Dent. Res. 100, 268-275 (2021).
• N. Rajabian, A. Shahini, M. Asmani, K. Vydiam, D. Choudhury, T. Nguyen, I. Ikhapoh, R. G. Zhao, P. Lei, S. T. Andreadis, “Bioengineered Skeletal Muscle as a Model of Muscle Aging and Regeneration”, Tissue Eng. Part A 27, 74-86 (2021).
• A. Jafari, N. Rajabian, G. Zhang, M. A. Mohamed, P. Lei, S. T. Andreadis, B. A. Pfeifer, C. Cheng, “PEGylated Amine-Functionalized Poly(epsilon-caprolactone) for the Delivery of Plasmid DNA”, Materials 13, 898 (2020).
• C. T. Brown, K. Nam, Y. Zhang, Y. Qiu, S. M. Dean, H. T. dos Santos, P. Lei, S. T. Andreadis, O. J. Baker, “Sex-dependent Regeneration Patterns in Mouse Submandibular Glands”, J. Histochem. Cytochem. 68, 305-318 (2020).
• R. Z. Samuel, P. Lei, K. Nam, O. J. Baker, S. T. Andreadis, “Engineering the mode of morphogenetic signal presentation to promote branching from salivary gland spheroids in 3D hydrogels”, Acta Biomater. 105, 121-130 (2020).
• Y. Y. Liu, P. Lei, S. Row, S. T. Andreadis, “Cadherin-11 binds to PDGFR beta and enhances cell proliferation and tissue regeneration via the PDGFR-AKT signaling axis”, Faseb J. 34, 3792-3804 (2020).
• S. M. Boroujeni, A. Koontz, G. Tseropoulos, L. Kerosuo, P. Mehrotra, V. K. Bajpai, S. R. Selvam, P. Lei, M. E. Bronner, S. T. Andreadis, “Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo”, Sci. Rep. 9, 9750 (2019).
• K. Nam, S. M. Dean, C. T. Brown, R. J. Smith, P. Lei, S. T. Andreadis, O. J. Baker, “Synergistic effects of laminin-1 peptides, VEGF and FGF9 on salivary gland regeneration”, Acta Biomater. 91, 186-194 (2019).
• A. Shahini, K. Vydiam, D. Choudhury, N. Rajabian, T. Nguyen, P. Lei, S. T. Andreadis, “Efficient and high yield isolation of myoblasts from skeletal muscle”, Stem Cell Res. 30, 122-129 (2018).
• G. Tseropoulos, S. M. Boroujeni, V. K. Bajpai, P. Lei, S. T. Andreadis, “Derivation of neural crest stem cells from human epidermal keratinocytes requires FGF-2, IGF-1, and inhibition of TGF-beta 1”, Bioeng. Transl. Med. 3, 256-264 (2018).
• A. Shahini, D. Choudhury, M. Asmani, R. G. Zhao, P. Lei, S. T. Andreadis, “NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings”, Stem Cell Res. 26, 55-66 (2018).
• K. Nam, C. S. Wang, C. L. M. Maruyama, P. Lei, S. T. Andreadis, O. J. Baker, “L1 Peptide-Conjugated Fibrin Hydrogels Promote Salivary Gland Regeneration”, J. Dent. Res. 96, 798-806 (2017).
• K. Nam, C. L. Maruyama, C. S. Wang, B. G. Trump, P. Lei, S. T. Andreadis, O. J. Baker, “Laminin-111-derived peptide conjugated fibrin hydrogel restores salivary gland function”, PLoS One 12, e0187069 (2017).
• V. K. Bajpai, L. Kerosuo, G. Tseropoulos, K. A. Cummings, X. Y. Wang, P. Lei, B. Liu, S. Liu, G. K. Popescu, M. E. Bronner, S. T. Andreadis, “Reprogramming Postnatal Human Epidermal Keratinocytes Toward Functional Neural Crest Fates”, Stem Cells 35, 1402-1415 (2017). PDF
• P. Mistriotis, V. K. Bajpai, X. Y. Wang, N. Rong, A. Shahini, M. Asmani, M. S. Liang, J. M. Wang, P. Lei, S. Liu, R. G. Zhao, S. T. Andreadis, “NANOG Reverses the Myogenic Differentiation Potential of Senescent Stem Cells by Restoring ACTIN Filamentous Organization and SRF-Dependent Gene Expression”, Stem Cells 35, 207-221 (2017).
• K. Nam, J. P. Jones, P. Lei, S. T. Andreadis, O. J. Baker, “Laminin-111 Peptides Conjugated to Fibrin Hydrogels Promote Formation of Lumen Containing Parotid Gland Cell Clusters”, Biomacromolecules 17, 2293-2301 (2016).
• N. Likhite, C. A. Jackson, M. S. Liang, M. C. Krzyzanowski, P. Lei, J. F. Wood, B. Birkaya, K. L. Michaels, S. T. Andreadis, S. D. Clark, M. C. Yu, D. M. Ferkey, “The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling”, Sci. Signal. 8, ra115 (2015).
• J. Moharil, P. Lei, J. Tian, D. P. Gaile, S. T. Andreadis, “Lentivirus Live Cell Array for Quantitative Assessment of Gene and Pathway Activation during Myogenic Differentiation of Mesenchymal Stem Cells”, PLoS One 10, e0141365 (2015).
• C. L. M. Maruyama, N. J. Leigh, J. W. Nelson, A. D. Mccall, R. E. Mellas, P. Lei, T. Andreadis, O. J. Baker, “Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters”, J. Dent. Res. 94, 1610-1617 (2015).
• S. Son, M. S. Liang, P. Lei, X. Z. Xue, E. P. Furlani, S. T. Andreadis, “Magnetofection Mediated Transient NANOG Overexpression Enhances Proliferation and Myogenic Differentiation of Human Hair Follicle Derived Mesenchymal Stem Cells”, Bioconjugate Chem. 26, 1314-1327 (2015).
• S. Alimperti, P. Lei, Y. Wen, J. Tian, A. M. Campbell, S. T. Andreadis, “Serum-Free Spheroid Suspension Culture Maintains Mesenchymal Stem Cell Proliferation and Differentiation Potential”, Biotechnol. Prog. 30, 974-983 (2014).
• R. Padmashali, H. You, N. Karnik, P. Lei, S. T. Andreadis, “Adherens Junction Formation Inhibits Lentivirus Entry and Gene Transfer”, PLoS One 8, e79265 (2013).
• A. D. Mccall, J. W. Nelson, N. J. Leigh, M. E. Duffey, P. Lei, S. T. Andreadis, O. J. Baker, “Growth Factors Polymerized Within Fibrin Hydrogel Promote Amylase Production in Parotid Cells”, Tissue Eng. Part A 19, 2215-2225 (2013).
• M. S. Liang, M. Koobatian, P. Lei, D. D. Swartz, S. T. Andreadis, “Differential and synergistic effects of mechanical stimulation and growth factor presentation on vascular wall function”, Biomaterials 34, 7281-7291 (2013).
• H. You, R. M. Padmashali, A. Ranganathan, P. Lei, N. Girnius, R. J. Davis, S. T. Andreadis, “JNK regulates compliance-induced adherens junctions formation in epithelial cells and tissues”, J. Cell Sci. 126, 2718-2729 (2013).
• S. Alimperti, P. Lei, J. Tian, S. T. Andreadis, “A novel lentivirus for quantitative assessment of gene knockdown in stem cell differentiation”, Gene Ther. 19, 1123-1132 (2012).
• J. H. Han, P. Mistriotis, P. Lei, D. Wang, S. Liu, S. T. Andreadis, “Nanog Reverses the Effects of Organismal Aging on Mesenchymal Stem Cell Proliferation and Myogenic Differentiation Potential”, Stem Cells 30, 2746-2759 (2012).
• J. Wang, P. Lei, S. T. Andreadis, T. J. Mountziaris, “DETECTION OF DNA HYBRIDIZATION VIA FLUORESCENCE INTENSITY VARIATIONS OF ZnSe-DNA QUANTUM DOT BIOSENSORS”, Anal. Lett. 45, 227-241 (2012).
• L. M. Lugo, P. Lei, S. T. Andreadis, “Vascularization of the Dermal Support Enhances Wound Re-Epithelialization by In Situ Delivery of Epidermal Keratinocytes”, Tissue Eng. Part A 17, 665-675 (2011).
• J. Tian, S. Alimperti, P. Lei, S. T. Andreadis, “Lentiviral microarrays for real-time monitoring of gene expression dynamics”, Lab Chip 10, 1967-1975 (2010).
• S. D. Raut, P. Lei, R. M. Padmashali, S. T. Andreadis, “Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays”, J. Control. Release 144, 213-220 (2010).
• P. Lei, R. M. Padmashali, S. T. Andreadis, “Cell-controlled and spatially arrayed gene delivery from fibrin hydrogels”, Biomaterials 30, 3790-3799 (2009).
• R. Singh, P. Lei, S. T. Andreadis, “PKC-delta binds to E-cadherin and mediates EGF-induced cell scattering”, Exp. Cell Res. 315, 2899-2913 (2009).
• J. Tian, P. Lei, S. G. Laychock, S. T. Andreadis, “Regulated insulin delivery from human epidermal cells reverses hyperglycemia”, Mol. Ther. 16, 1146-1153 (2008).
• K. G. Cornwell, P. Lei, S. T. Andreadis, G. D. Pins, “Crosslinking of discrete self-assembled collagen threads: Effects on mechanical strength and cell-matrix interactions”, J. Biomed. Mater. Res. Part A 80A, 362-371 (2007).
• P. Lei, A. Ogunade, K. L. Kirkwood, S. G. Laychock, S. T. Andreadis, “Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: Implications for treatment of diabetes”, Tissue Eng. 13, 2119-2131 (2007).
• B. G. Bajaj, P. Lei, S. T. Andreadis, “Efficient gene transfer to human epidermal keratinocytes on fibronectin: In vitro evidence for transduction of epidermal stem cells”, Mol. Ther. 11, 969-979 (2005).
• P. Lei, S. T. Andreadis, “Stoichiometric limitations in assembly of active recombinant retrovirus”, Biotechnol. Bioeng. 90, 781-792 (2005).
• P. Lei, B. Bajaj, S. T. Andreadis, “Retrovirus-associated heparan sulfate mediates immobilization and gene transfer on recombinant fibronectin”, J. Virol. 76, 8722-8728 (2002).
• P. Lei, B. Bajaj, S. T. Andreadis, “Retrovirus-associated heparan sulfate mediates immobilization and gene transfer on recombinant fibronectin (vol 76, pg 8722, 2002)”, J. Virol. 76, 11176-11176 (2002).
• B. Bajaj, P. Lei, S. T. Andreadis, “High efficiencies of gene transfer with immobilized recombinant retrovirus: Kinetics and optimization”, Biotechnol. Prog. 17, 587-596 (2001).