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Chris Mancinelli is a Senior Principal Engineer at Shire Pharmaceuticals in their Drug Product Manufacturing Science & Technology group located in Chesterbrook, PA. In this role, Chris leads commercial chemistry manufacturing and control (CMC) teams to support new worldwide market launches of Shire products as well as providing technical expertise to achieve and maintain robust commercial processes.
Previously, Chris worked at Merck & Co., where he most
recently served as Director of Engineering in the Diversified
Brands/Branded Generics business unit from 2012-2015. In this role
he led teams overseeing CMC development through launch for new and
in-line products throughout the Emerging Markets and Japan. During
his career with Merck starting in 2003, he held several positions
in process development responsible for scale-up, tech transfer,
validation and commercial manufacturing. In 2007, Chris took on a
four-year assignment in Ireland where he was the Technical Lead in
the newly-formed Pharmaceutical development group charged with
establishing capabilities for drug product formulation processing
and development at the site. Chris then started up a Technical
Operations Group which provided technical support to all aspects of
production preparation, execution, and troubleshooting. He played a
key role in leading the Pharmaceutial Operations facility through
the Irish Medicines Board licensing inspections, and in preparation
and execution of facility activities for a new product launch,
including co-leading the FDA pre-approval inspection.
Chris received a BS in Chemical Engineering from the University at Buffalo in 1998, and a MS in Colloids, Polymers and Surfaces and PhD in Chemical Engineering from Carnegie Mellon University with emphasis in the field of Tribology in 2003. Over the years, Chris has contributed his leadership and expertise to industry organizations to influence current practices and mentor young engineers entering the pharmaceutical industry. He is an active member of the American Institute of Chemical Engineers and the American Chemical Society. Chris is also an avid beekeeper and sits on the Executive Board of the Montgomery County Beekeepers Association of PA.
Chris often thinks about his days at UB and the deep fundamental education obtained by the many dedicated and brilliant faculty and staff in the Chemical Engineering department. Also not to forget the many long nights spent at the library with the study crew working through problems together, the engineering summer internship program which combined classroom learning with real life industrial experiences, roller blading around the campuses at all hours of the day and night, and generally enjoying an environment both highly conducive to learning and yet also enabling individual growth beyond science and engineering. "I owe a lot of where I am today to the strong foundation built at UB."